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For control, the calibration set consists of the [GSH] and [GSSG] measurements at PN11, PN13 and PN15, and the validation set contains the data at PN15, PN17 and PN28
Additionally, the expression of the CALCB and INPP5B genes in various brain regions was also found to be significantly associated with migraine risk, with consistent effect directions (detailed data available in Table S7)
2023;9:eade9585
Importantly, a recent DR-focused clinical study reported higher serum irisin levels in patients without retinopathy compared with those with DR, even after adjustment for HbA1c and diabetes duration, supporting a potential protective or compensatory role (252)
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