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In clinical trials, adults lost about 15% of their body weight on average with semaglutide and roughly 2022% with tirzepatidebut those are trial averages achieved alongside lifestyle changes, not a guaranteed outcome for any one person
Coverage policies vary widely: a KFF 2025 employer survey found 43% of firms with 5,000+ workers now cover GLP-1 weight-loss drugs (up from 28% in 2024) ( [6] ), yet many patient advocacy reports and journalists note patients cutting doses or resorting to unapproved sources due to cost ( [4] ) ( [7] )
Rybelsus European Public Assessment Report (EPAR)
Rotating the injection site between your abdomen, thigh, and upper arm can also help prevent soreness or irritation
[8] Semaglutide (the active ingredient in Wegovy) does not affect the absorption of the oral contraceptive pill, so it can be used alongside your treatment
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