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As clinical evidence supporting the synergy of combination treatments grows, more trials are being designed to evaluate their long-term benefits and safety
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PMC Article PMC4508379
NAD+/NADH ratio assays, SIRT1 activity assays, and mitochondrial respiration measurements (such as oxygen consumption rate via extracellular flux analysis) are standard methods for studying this combination's proposed effects in cell-based models, typically comparing single-compound and combined-compound treatment conditions against untreated controls
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