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Since oral glutathione is poorly absorbed, a liposomal form using nanotechnology is recommended
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Acute complete depletion may rapidly amplify oxidative stress and cell injury, whereas more gradual depletion appears to allow for more selective redox remodeling without overwhelming stress responses, although further studies including comprehensive transcriptomic and epigenomic analyses will be necessary to dissect the differential regulatory networks altered by different modes of GSH depletion
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An improved understanding of the regulatory interfaces that exist between blood and brain may provide novel and more effective strategies to treat neurological disorders
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Published April 23, 2014
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