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In the APP/PS1 model, somatostatin (SOM) interneurons near amyloid plaques become hyperactive, while parvalbumin interneurons are hypoactive, leading to an excitation-inhibition imbalance (Algamal et al., 2022)

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Factors such as soil depletion, processed foods, and lifestyle choices can result in magnesium deficiency, which may lead to a range of health issues, including fatigue, muscle cramps, anxiety, and weakened immune function

It can bind to vitamins or other good nutrients, and to medications, making those medications less effective. He recommends taking oral medications at least three hours before or after ingesting anything with activated charcoal in it, whether thats an oral contraceptive or an aspirin