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Congeners may also slow the metabolism of alcohol, which can prolong your symptoms ( Drinks that are low in congeners include vodka, gin, and rum ( Meanwhile, tequila, whiskey, and cognac are all high in congeners, with bourbon whiskey containing the most ( In one older study, 95 young adults drank enough vodka or bourbon to reach a breath alcohol concentration of 0.11%

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If fasting glucose is trending upward, if IGF-1 exceeds normal ranges, or if side effects are becoming unmanageable, this is the point to reassess the protocol

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The concern is physiological and behavioral rather than a classic drug-drug interaction