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By helping control blood glucose, metformin reduces the risk of diabetes-related complications and supports long-term health
Mechanistically, we demonstrated that intracellular BPC157 interacts with the E3 ubiquitin ligase adaptor FBXO22 via its proline residue at position 3
Acknowledgements This work was supported by the National Science and Technology Council, Taiwan (grant number NSTC 111-2320-B-002-037-MY3 to F-JL) and National Taiwan University (grant numbers 110L7243, 111L7218, and 113L894803 to F-JL)
In contrast, larger linear peptides, such as LL-37 and AW1, may exhibit strong antimicrobial activity but often face challenges related to delivery and stability