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141,142 Recurrent somatic mutation of residues are mainly located at enzymatic active sites that bind to isocitrate, typically at R132 including R132H, R132L, R132S, R132C, and R132G in IDH1, and R140Q or R172K in IDH2
CS has been shown to induce a number of different antioxidant defenses including the expression of enzymes and transcription factors that lead to increased synthesis of GSH [14]
Improve ATP (adenosine triphosphate) synthesis vital for cellular energy supply
Retinitis Pigmentosa: The extensive research of Dr
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