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Allergic reactions (though rare, they may include rash, itching, or difficulty breathing)

General safety observations from published health sources show: Oral glutathione is well tolerated in moderate doses Long-term use does not suppress natural production No evidence suggests dependency or rebound effects Side effects are rare and usually mild Mild side effects, when they occur, may include bloating or headache, often linked to excessive dosing rather than duration of use

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Crucially, the researchers noted that one month after stopping the supplement, glutathione levels returned to baseline, proving that continuous, sustained intake is required to maintain the therapeutic benefits