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Research has linked glutathione deficiency to:[1][2] Neurological conditions Alzheimers, Parkinsons, cognitive decline Liver disease the organ that makes and uses the most glutathione Cardiovascular disease oxidative damage to blood vessels Diabetes and insulin resistance glutathione protects pancreatic cells Autoimmune conditions impaired immune regulation Chronic inflammation the root of most modern disease Cancer compromised cellular protection and detoxification One study found that glutathione status directly parallels telomerase activity a key marker of cellular aging and longevity.[1] Higher glutathione levels correlate with better health across nearly every measure researchers have looked at

Notably, researchers have documented that the peptide appears to upregulate NO production when it is deficient and downregulate it when excessive, suggesting a modulatory rather than simply stimulatory relationship

Differential effect of dietary selenium on the long-term neurotoxicity induced by MDMA in mice and rats

Toxicity of repeated oral intake of organic selenium, inorganic selenium, and selenium nanoparticles: A review

595 A study suggests that the activation of PARP may lead to cell death through ATP consumption and enhancement of the inflammatory cascade in mice