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FDA warned consumers that Reumofan Plus, marketed as a natural dietary supplement for pain relief and other serious conditions, contains several active pharmaceutical ingredients not listed on the label that could be harmful
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doi: 10.1017/S0029665111000346

The small intestine relies on a natural "cleaning wave" called the migrating motor complex (MMC)

Once a drug receives FDA approval, healthcare providers can prescribe it for those approved uses

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