The people who achieved the best results were the ones who stayed consistent through the early weeks when effects were subtle
In a separate study , published in JAMA in August 2025, the same researchers found that, across ages, GLP-1s were associated with lower risk of some obesity-related cancers, such as endometrial, ovarian, and meningioma cancers, but with an increased risk of kidney cancer, and nonsignificant changes for several other cancers
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PubMed , JAMA , vol
One woman claims that it made her life hell. All report ongoing nausea and vomiting as well as other health issues even after they stopped taking the drugs