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Human leucocyte antigen (HLA)-C-specific KIRs can bind zinc, and chelating zinc reverses their inhibitory function, suggesting that zinc is essential for their activity

Insufficient human clinical trials have led to a lack of data to determine a safe dose

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Scutellarin can down-regulate the Wnt/-cyclone in the signaling pathway and decrease the expression of TNF- and IL-6 in serum, improving colitis-related colorectal cancer (107)