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At USD 1,349 per month list price for Wegovy and USD 1,059 for Zepbound, monthly GLP-1 obesity drug costs create absolute financial barriers for the 62% of obesity patients enrolled in Medicaid, Medicare, or underinsured commercial plans without anti-obesity medication benefits

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After the cells reached ~ 80% confluence under normal culture conditions, the medium was changed to glucose-free DMEM (Gibco) and the dish was placed in an anaerobic chamber (5% CO2, 95% N2) to induce OGD-related cell injury