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53 Pancreatic and Hepatobiliary Events Pancreatitis and Pancreatic Disorders It has been suggested that GLP-1 RAs may influence pancreatic physiology through multiple mechanisms, including effects related to rapid weight loss and gallstone formation, which have been hypothesized to contribute indirectly to pancreatitis risk
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Additionally, GLP-1 receptor agonists act on appetite centres in the brain, particularly the hypothalamus, leading to reduced food intake and promoting weight loss
