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( A D ) Urine volume, urine sodium, urine chloride, and urine protein in normotensive control Glp1r VSM+/+ and Glp1r VSM/ male mice treated acutely with semaglutide (10 g/kg) 60 minutes prior to water gavage

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Once-weekly formulations of semaglutide (Wegovy) and daily liraglutide (Saxenda) are FDA-approved for weight loss in patients who are overweight or obese while other existing formulations are approved solely for patients with type 2 diabetes, although it is likely that broader indications for weight loss (regardless of glycemic status) are forthcoming

If FITIV's weight trend shows more than 2 percent loss in a week, eat a bit more, particularly more protein, rather than pushing the deficit further