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First is to improve upstream pathways such as methylation

Dihexa was developed as a structurally modified analogue of angiotensin IV and retains key features of the parent scaffold while incorporating modifications designed to alter physicochemical and pharmacological properties

Patients with idiopathic trigeminal neuralgia have a sharper-than-normal trigeminal-pontine angle and trigeminal nerve atrophy

Influence of the N-terminus acetylation of Semax, a synthetic analog of ACTH (4-10), on copper(II) and zinc(II) coordination and biological properties