The insulin resistance paradox This is the primary safety concern, and it deserves detailed explanation
doi:10.1111/j.1600-0781.2011.00557.x
Some patients who have received too much Botox, depending on the location of the injections, have developed facial and eyelid drooping, bruising, jaw weakness, headache, neck or back pain, and back weakness
PMID: 27181790
Riboflavin also supports the antioxidant defense system by aiding the regeneration of other antioxidants, such as glutathione, from oxidized glutathione (GSSG), since riboflavin, in the form of FAD, is necessary for glutathione reductase to play its role in converting GSSG (, )