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Over 29 days of treatment, the peptide inhibited pulmonary artery muscularization (the thickening and stiffening of pulmonary arteries that drives this condition), prevented right heart hypertrophy (the enlargement of the right ventricle that occurs when it has to pump against increased resistance), and significantly decreased mortality

This inherent protective quality is not confined to a single organ system but rather exerts a stabilizing influence across various tissues, providing the mechanistic foundation for its dual action in both the gastrointestinal tract and the central nervous system

Drug interaction studies are essential to understand how these peptides may interact with commonly prescribed medications

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No experimental datasets were generated during the current study