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Resistance It is known from a disease called diabetes mellitus, that there can be resistance to the actions of the hormone insulin the main regulator of blood glucose concentrations in many individuals
Normally, Vitamin B12 absorption requires a protein called intrinsic factor, produced in the stomach
The evidence is preclinical mouse and cell studies
However, modern advancements in supplement formulation have significantly improved the bioavailability of oral B12, making it a more effective option than ever before
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