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2.2.4 Endoplasmic reticulum stress Endoplasmic reticulum (ER) stress plays a central role in metabolic, vascular, and neuroinflammatory disorders

By modulating macrophage polarization towards an M2 subtype, GLP-1RAs can inhibit inflammation occurring in the vessel lumen, an action which would alleviate the progression of atherosclerosis (Figure 2)

J Neuroimmunol 386:578514

Koester-Weber, T

Basal, maximal, and ATP-linked oxygen consumption rates (OCRs) were quantified using the XF Cell Mito Stress Test Kit (Agilent) on a Seahorse XF96 bioenergetics analyzer (Agilent)