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Healthy Fats: Sustained GLP-1 Through Bile Acid Signaling Dietary fats trigger GLP-1 release through multiple pathways direct activation of fatty acid receptors on L-cells (GPR40 and GPR120), and indirectly through bile acid signaling via the TGR5 receptor
Researchers hypothesize that these mechanisms could adjust synaptic plasticity and neuronal communication in experimental systems
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Individuals with PWS have elevated levels of ghrelin and oxytocin, both of which are involved in addictive behaviors
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