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It appears to be safe in ongoing studies, but long-term effects are still being researched
2.9 Cell culture and treatment Mouse colon epithelial cells (MCECs) were cultured in high-glucose Dulbeccos Modified Eagle Medium, supplemented with 10% fetal bovine serum and 1% penicillin-streptomycin (P/S), in a humidified incubator with 5% CO 2 at 37C
Failure to respond to tolvaptan is very rare in SIADH, and linked to poorly differentiated malignancy with low survival rates
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