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Proton Pump Inhibitors (PPIs) and Histamine 2 Receptor Antagonists (H2RAs) are two groups of drugs which act by reducing the gastric acid secretion
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The oxidative damages of biomolecules specifically of DNA due to the accumulation of hydroperoxides and other ROS ultimately lead to the loss of cell viability or cell death through various death mechanisms like apoptosis, autophagy, necrosis, ferroptosis, and mitotic catastrophe (Fig
Its a synthetic version derived from a protein naturally found in gastric juice
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