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Individual results depend on factors including starting weight, dose, lifestyle changes, and adherence to treatment
When GLP-1 binds to these receptors, it can shift macrophages from a pro-inflammatory M1 phenotype to an anti-inflammatory M2 phenotype, inhibit the production of pro-inflammatory cytokines like TNF-, IL-1, and IL-6, increase anti-inflammatory adiponectin, and inhibit NF-B, a key regulator of pro-inflammatory gene expression
These include nausea, vomiting, and diarrhea, which are common to all incretin mimetics
Milligrams measure the weight of the active medication
Glucagon-related peptide 1 (GLP-1): hormone and neurotransmitter
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