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Modern injections use 32-gauge needles (extremely thin), inject under the skin rather than into muscle, and many people find them far less uncomfortable than anticipated
Hair shedding can happen during weight loss for several reasons, including rapid weight loss, low protein, low calories, stress, iron issues, thyroid issues, or other health factors
More serious adverse effects include pancreatitis, gallbladder disease (cholelithiasis, cholecystitis), and acute kidney injury (particularly with severe dehydration from gastrointestinal symptoms)
At this time, there are no defined criteria for triggering a switch from semaglutide to tirzepatide
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