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The aims of this review are (1) to provide an overview of the clinical and biological overlap between neuropsychiatric long COVID and other fatigue-associated neuropsychiatric disorders, (2) to examine the shared molecular mechanisms of fatigue and depressive symptoms involving acetylcarnitine metabolism, and finally (3) to review the current evidence on acetylcarnitine supplementation studies as a treatment for fatigue-associated syndromes and pharmacological aspects of acetylcarnitine supplementation to provide a conceptual foundation for acetylcarnitine supplementation in neuropsychiatric long COVID syndrome

The acetyl group of ALCAR is used to produce the antioxidant glutathione (GSH), reducing oxidative stress, and protecting cells against lipid peroxidation [23, 24]

Research shows enhanced granulation tissue formation, improved re-epithelialization, increased collagen deposition, and superior dermal remodeling through VEGF pathway activation

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Under-dosing may produce no results, while over-dosing can lead to unwanted side effects or waste expensive material