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4.1 Cardiac surgery (heart and systemic organ protection) Cardiac surgeries like coronary artery bypass grafting (CABG) or valve replacement commonly utilize cardiopulmonary bypass (CPB), which triggers a significant systemic inflammatory response due to blood contact with artificial surfaces, ischemia-reperfusion of the heart, and global hypothermia/rewarming (166, 167)
DOI:10.1007/ s11033-012-2323-3 [ Links ] 65
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