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Clinical Insight: This regeneration relies on enzymes like glutathione reductase
Am J Physiol Gastrointest Liver Physiol 2006;290:G852-G858
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Researchers intending to work with the lyophilised version should ensure access to DMSO or a similar solvent for proper handling
If levels do not correlate well, consider either dosing solely based on free phenytoin levels (if these can turn around rapidly enough) or avoiding phenytoin altogether
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