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Drug repurposing based on a Quantum-Inspired method versus classical fingerprinting uncovers potential antivirals against SARS-CoV-2 including vitamin B12

doi: 10.3389/fphar.2022.977062 9 MaGZhangZLiPZhangZZengMLiangZet al

Polymorphisms in various genes involved in vitamin B 12 metabolism, including the genes encoding the intrinsic factor-cobalamin receptor (60) and the holo-transcobalamin receptor (61), have been associated with increased NTD risk in some studies

The induction of HLCs in vitro requires weeks-long cytokines irrigation

Additionally, in pyrimidine synthesis, the conversion of uridine monophosphate (UMP, the primary precursor) takes place, leading to the formation of deoxyuridine monophosphate (dUMP)