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In particular, autophagy is deregulated in PD brains 17
Dudum accused Novo of attempting to control how clinicians at Hims make decisions
The overactivation of microglia leads to the release of pro-inflammatory factors such as Interleukin-1 beta (IL-1), Tumor Necrosis Factor-alpha (TNF- ), and Interleukin-6 (IL-6), which directly damage dopaminergic neurons in the substantia nigra pars compacta (SNpc) (McCarty and Lerner, 2020)
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