Mankin, H
Polymeric nanoparticles Polymeric nanoparticles are generally synthesized from natural and synthetic biocompatible and biodegradable polymers with hydrophilic and hydrophobic properties, such as natural hydrophilic polymers, including proteins (e.g., albumin and gelatin) and polysaccharides (e.g., chitosan and alginate) (Chakravarty and Vora, 2020), and hydrophobic polymers, including polymethacrylates, poly(lactic-co-glycolic acid) (PLGA), polystyrene, poly(N-isopropyl acrylamide), poly(lactic acid) (PLA), poly(isobutyl cyanoacrylate) (PICA), and poly(hexyl cyanoacrylate) (Smola et al., 2008
A misfolded or partially unfolded protein exposes hydrophobic surface, and that surface nucleates further aggregation
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Dipeptidylpeptidase inhibition is associated with improvement in blood pressure and diastolic function in insulin-resistant male Zucker obese rats