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Urinary F2-isoprostane is the gold standard marker of lipid peroxidation, reliable for assessing oxidative stress
It is not clear how to achieve this goal, which presumably would involve convincing dysfunctional disease-astrocytes to physically give up their established connections with motor neurons and be replaced by healthy astrocytes, if not occurring spontaneously (Fig
There are several categories of enzymes involved in the metabolism of lipophilic xenobiotics and their conversions into less toxic compounds exhibiting increased hydrophilicity (Figure 2)
Riboflavin deficiency is associated with selective preservation of critical flavoenzyme-dependent metabolic pathways
19, 50 Weibe etal
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