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HUBERMAN: In order to find out the lethal dose of something, as you can imagine, unfortunately, the way these studies are done is they give animals more and more, that is higher and higher doses of a given compound, find out at what point about 50% of the population of those animals starts to die, and then that's the so-called LD50, or at least that's one crude way of describing it

The 0.5mL option works if you have a high-quality syringe with clear markings at the 10-unit level, but cheaper syringes can make that small volume harder to measure accurately

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More significant changes, such as improvements in body composition and muscle tone, typically become more apparent after two to three months of consistent use

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