Adv Healthc Mater 14:2402376 Nabipour H, Rohani S (2024) Metalorganic frameworks for overcoming the blood-brain barrier in the treatment of brain diseases: a review
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This drug is a glucagon-like peptide-1 (GLP-1) receptor agonist, which mimics the natural hormone GLP-1, enhancing insulin secretion and promoting satiety
CntA/B is a notoriously hard enzyme to study, but once it was stabilized, we were able to gain insight into how CntA perceives its L-carnitine substrate with a 3D crystal structure model, and by studying the complete electron transfer pathway, we could see how the protein is able to turn over TMA