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Both groups saw comparable moderate decreases in serum triglycerides and cholesterol
Moreover, inflammatory mediators, such as Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) and Tumor necrosis factor-alpha (TNF-) increased, while pivotal proteins involved in dendritic and synaptic development, such as Synaptophysin (SYP), postsynaptic density protein 95 (PSD95) and brain-derived neurotrophic factor (BDNF) decreased in APP/PS1 mice
Confusion and memory loss
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Nitric Oxide Signaling Pathways BPC-157 interacts with nitric oxide synthase (NOS) systems and is believed to modulate NO release, impacting vascular tone, inflammation, and wound oxygenation in experimental studies
