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Lastly, glutamine oxidation supports redox homeostasis by supplying carbon to malic enzymes, which produce NADPH

Hence, it can be speculated, that the myocardial scarring in some PCD patients combined with an oxidative or metabolic stress can be the substrate of the increased risk of SCD in untreated patients with PCD

Scientists now recognize that aging reflects a set of measurable biological processes that influence how cells respond to stress, repair damage, and maintain normal function