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Although the ELIXA studythe only CVD outcome trial of GLP-1 RAs published to datereported a neutral cardiovascular effect of lixisenatide, the potential cardiovascular benefits of GLP-1 RAs should not be overlooked, because high-risk subjects with established CVD were recruited in this study to delineate its cardiovascular safety within a short-term period

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Over the past decade, it has been demonstrated that myocardial structure, cardiomyocyte function, and intramyocardial signaling undergo specific alterations in heart failure with preserved ejection fraction (HFpEF)

Polyphenols from aerial parts of Polygonum bellardii and their biological activities