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Da die Evidenz fr Kombinationen berwiegend auf theoretischen berlegungen und anekdotischen Berichten beruht, ist hier besondere Zurckhaltung angebracht

Functional assessment may require mitochondrial respiration, proton-leak measurements, tissue temperature, oxygen consumption, adrenergic responsiveness, cold challenge, or whole-body energy-expenditure measurements

Developing drugs for metabolic dysfunction-associated steatohepatitis (MASH) has been a surprisingly challenging task

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In other studies, phenytoin was used as a reagent to treat mouse embryos because it causes oxidation of DNA, proteins, and lipids, likely due to increased production of OH radicals (89, 90)