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Mouse islets were transduced 24 hours prior to imaging with an adenoviral SNAP/FLAG-hGLP-1R vector (custom made by VectorBuilder) at a MOI of 1 and subsequently labelled for 10 minutes at 37 C with SNAP-Surface Alexa Fluor 647 before 5-minute stimulation with indicated agonists and imaging of whole islets in the same microscope as above

No single Chinese sponsor dominates the way Hanmi or Sanofi do

At 15 mg/mL concentration (30 mg vial + 2 mL bac water), the 12 mg dose draws 80 units on a U-100 syringe

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GI side effects (nausea, vomiting) are titration-dependent