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The compound simultaneously activates three receptors that have historically been engaged separately or in pairs: GLP-1R (Glucagon-Like Peptide-1 Receptor)

That said, GLP-1 medications arent recommended during pregnancy

16 Chronic stress signaling even appears to inhibit glymphatic function, leading to a buildup of neurotoxins that may contribute to neurologic disorders

The Heart Disease Study of Semaglutide in Patients with Type 2 Diabetes (SOUL) is a more extensive and extended phase 3 CVOT presently being conducted, and results are expected in 2024 [55]

While these reactions are uncommon, its always best to prioritize your safety and ensure all providers are kept in the loop