The distinction matters enormously for anyone trying to make informed decisions about their long-term semaglutide treatment
The STEP trials found that people who stayed on semaglutide for two years maintained their weight loss and continued to show improvements in HbA1c, fasting glucose, triglycerides, and inflammatory markers
For example, aspirin, which can help alleviate pain, can also cause gastric reflux
The main risks are gastrointestinal discomfort for some, or reactions if you have sensitivities to ingredients like carnitine or methionine
Furthermore, NRF2 was also found to regulate the expression of thioredoxin 1 (TXN1) and thioredoxin reductase 1 (TXNRD1), which can reduce oxidized protein thiols [25, 26]