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The temperature of pathway A is always coincident with the number of hits in the pathway, implying that its null distribution is the hypergeometric distribution, to which a one-tailed temperature comparison is made

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Wilson disease gene carriers (ATP7B heterozygotes, roughly 1 in 90 people) may be particularly sensitive

Long-term, chronic use of marijuana is associated with impaired thinking and memory, and even a loss of IQ among teenage users