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These medications are FDA-approved primarily for the treatment of type 2 diabetes mellitus, with some formulations also approved for chronic weight management in adults with obesity or overweight with at least one weight-related comorbidity
In clinical trials, Mounjaro and Semaglutide have consistently demonstrated substantial weight loss benefits
Most people with treated hypothyroidism can safely use GLP-1 or GLP-1/GIP medications under medical supervision, provided they do not have certain rare thyroid cancer risks
Consequently, the EMA recommended updating the product information for semaglutide medicines to reflect this risk
They may be fortified from small amounts to more than 200% of the RDA
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