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Approximately three months after recovering from his acute anemia, the patients glucose-6-phosphate dehydrogenase level was tested and was 5.2 (reference range: 9.9 - 16.6 U/g Hb.) Discussion This case exemplifies the importance of considering G6PD deficiency as an etiology of acute hemolytic anemia when administering medications known to increase oxidative stress, such as rasburicase
Peptide research continues revealing new mechanisms of action
Oxidative stress induces subtle changes in intracellular pathways including redox signaling at lower levels, but it causes cellular dysfunction and damage at higher levels
G.AnderssonP.JohanssonE
In the PD Drosophila model, overexpression of Nrf2 and knockdown of Keap1 alleviate the decline in locomotor ability (170)
