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Glucagon affects energy expenditure and fat metabolism through different pathways than GLP-1 or GIP

injection of d-glucose (1 or 2 g kg 1 , 10 ml kg 1 ), insulin (1.0 or 1.5 IU kg 1 , 10 ml kg 1 ) or sodium pyruvate (2 g kg 1 , 10 ml kg 1 ), and blood samples were collected at 15240 min

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GLP-1 medications, such as semaglutide (the active ingredient in Ozempic and Wegovy), have gained global attention for their ability to help people lose significant weight while improving insulin sensitivity and reducing appetite