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An example week at the 2.5 mg initiation step: The documented protocol allows the injection day to be moved if needed as long as doses stay at least several days apart, but for research clarity a fixed weekday is cleanest
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The MHRA has not issued specific warnings about B12 toxicity from supplements, reflecting the vitamin's excellent safety profile in the general population
doi: 10.1136/annrheumdis-2012-201526 294 KarouzakisERazaKKollingCBuckleyCDGaySFilerAet al
![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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