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Obesity and PsA have mutually reinforcing mechanisms Excessive adipose tissue expansion induces low-grade systemic inflammation 3 Dysfunctional adipose tissue acts as an endocrine organ that secretes proinflammatory mediators relevant to PsA pathogenesis 4, 5 Obesity increases mechanical stress on joints, resulting in the microtrauma associated with PsA pathogenesis 4,5 Functional disability in PsA may reduce physical activity, favoring further weight gain 4 b Proposed mechanisms are based on current evidence and remain hypothetical
10.1016/S0891-5849(02)00976-0
Blood sugar levels stabilize further, blood pressure typically drops 4-6 points systolic, and triglycerides show meaningful reductions
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But understanding that the labels reflect an absence of data rather than the presence of danger is important context for any mother evaluating her options with her healthcare provider
