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DOI: 10.1021/jm00394a033 MC4R Pathway Research Pre-clinical studies using MT-2 as an MC4R agonist tool compound have examined its effects on hypothalamic appetite circuits, food intake, body weight regulation, and metabolic parameters in rodent models

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The government department doesn't give a timeline regarding when generic forms of these drugs will be approved, but Mina Tadrous, associate professor of pharmacy at the University of Toronto, told CBC News that generics might be available by this summer or early fall