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Indeed, flux analysis showed that, similarly to GSH-sufficient MZB, Gclc -deficient FoB at rest showed decreased amounts of mitochondria-derived ATP (Fig

However, it is essential to note that GSH levels in both dose groups generally returned to baseline levels after a one-month washout period, suggesting that continuous supplementation is necessary to maintain elevated GSH levels

In this context, the focus lies not on any direct peptide-to-muscle effect, but on how receptor-driven endocrine signaling remodels downstream muscle biology [6]

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